Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 642
interventional 532
Observational 93
Registry 17

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 180
Drug|Radiation 55
Drug|Procedure|Radiation 32
Procedure 32
Other 21
Biological 19
Device 19
Drug|Procedure 19
Biological|Drug 18
Drug|Other 17
Radiation 17
Drug|placebo 15
Dietary Supplement 9
Drug|Other|Radiation 6
Procedure|Radiation 5
Biological|Drug|Other 4
Biological|Drug|Procedure|Radiation 4
Drug|Other|Procedure|Radiation 4
Biological|Drug|Procedure 3
Biological|Drug|Radiation 3
Genetic 3
Other|Procedure 3
Behavioral 2
Biological|Drug|Other|Procedure 2
Biological|Drug|placebo 2
Combination Product|Drug 2
Device|Drug|Radiation 2
Device|Other 2
Other|Radiation 2
Behavioral|Drug 1
Behavioral|Drug|Genetic|Other|Procedure 1
Behavioral|Drug|Other 1
Behavioral|Drug|placebo 1
Behavioral|Other 1
Behavioral|Procedure 1
Behavioral|Radiation 1
Biological|Combination Product 1
Biological|Device 1
Biological|Drug|Genetic|Other|Procedure|Radiation 1
Biological|Drug|Other|Procedure|Radiation 1
Biological|Drug|placebo|Radiation 1
Biological|Other|Procedure 1
Biological|Procedure 1
Biological|Radiation 1
Combination Product|Other|Procedure 1
Device|Drug 1
Device|Drug|Procedure 1
Device|Other|Procedure 1
Device|Procedure 1
Diagnostic Test 1
Diagnostic Test|Drug 1
Dietary Supplement|Other 1
Drug|Genetic 1
Drug|Genetic|Other 1
Drug|Genetic|Other|Procedure|Radiation 1
Drug|Genetic|Procedure 1
Drug|Genetic|Procedure|Radiation 1
Drug|placebo|Radiation 1
Genetic|Radiation 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 222
China 105
NA 21
France 17
Germany 16
Netherlands 16
Japan 13
United Kingdom 13
United States|Canada 9
Canada 7
Korea, Republic of 7
Taiwan 7
Italy 5
Spain 4
Denmark 3
Ireland 3
Sweden 3
Switzerland 3
United States|Puerto Rico 3
Belgium 2
Ireland|Sweden 2
United States|Puerto Rico|South Africa 2
Australia 1
Australia|Belgium|Germany|Netherlands|Switzerland|United Kingdom 1
Australia|Canada|New Zealand|United Kingdom 1
Austria 1
Austria|France|Germany|Hungary|Switzerland 1
Belgium|France|Germany|Netherlands 1
Bosnia and Herzegovina|Croatia|Korea, Republic of|Spain|Taiwan|United Kingdom 1
Brazil 1
Canada|China|Croatia|India|Pakistan|South Africa|Thailand 1
China|Korea, Republic of|Malaysia|Taiwan 1
China|Korea, Republic of|Taiwan 1
China|Malaysia|Philippines|Thailand 1
Croatia 1
Cuba 1
Denmark|France|Ireland|United Kingdom 1
France|Spain 1
Germany|Netherlands 1
Greece 1
India 1
Japan|Korea, Republic of|Taiwan 1
Japan|United States|Denmark|Germany|Italy|Korea, Republic of|Taiwan|United Kingdom 1
Netherlands|Switzerland 1
Norway 1
Norway|Sweden 1
Poland 1
Russian Federation 1
United Kingdom|United States|Belgium|Denmark|Sweden 1
United States|Argentina|Australia|Brazil|Canada|Chile|China|Colombia|Costa Rica|Denmark|France|Germany|Guatemala|Hong Kong|Japan|Korea, Republic of|Malaysia|Peru|Romania|Russian Federation|South Africa|Spain|Taiwan|Thailand|Turkey|United Kingdom 1
United States|Argentina|Australia|France|Hungary|New Zealand|Poland|Romania|Russian Federation|Slovakia|Turkey|United Kingdom 1
United States|Argentina|Belgium|Canada|Czechia|Denmark|Finland|France|Germany|Hungary|Israel|Italy|Japan|Mexico|Netherlands|Poland|Puerto Rico|Russian Federation|Spain|United Kingdom 1
United States|Australia|Belgium|Czechia|France|Germany|Italy|Korea, Republic of|Poland|Spain 1
United States|Australia|Belgium|France|Hungary|Italy|Poland|Spain|United Kingdom 1
United States|Australia|Brazil|Chile|China|France|Germany|Guatemala|Ireland|Israel|Italy|Japan|Korea, Republic of|New Zealand|Poland|Russian Federation|Spain|Turkey|Ukraine|United Kingdom 1
United States|Australia|Canada|Japan|Korea, Republic of|New Zealand|Taiwan 1
United States|Belgium|Canada|Czechia|Germany|Greece|Italy|Spain|Sweden|Turkey|Ukraine 1
United States|Belgium|Canada|Spain 1
United States|Belgium|Denmark|Hungary|United Kingdom 1
United States|Canada|France|Netherlands 1
United States|Canada|Japan|Korea, Republic of|Singapore|Taiwan 1
United States|Canada|Puerto Rico 1
United States|Chile|China|Denmark|Estonia|France|Hong Kong|Hungary|Italy|Korea, Republic of|Russian Federation|Taiwan|Turkey 1
United States|China|France|Italy|Japan|Korea, Republic of|Poland|Puerto Rico|Romania|Russian Federation|Spain|Taiwan|Turkey|United Kingdom 1
United States|France|Germany|Korea, Republic of|Netherlands|Spain|Taiwan|United Kingdom 1
United States|France|Italy|Japan|Singapore|Spain 1
United States|Germany 1
United States|Germany|Japan|Korea, Republic of|Switzerland|Taiwan 1
United States|Japan 1
United States|Taiwan 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 326
2 40
3 21
4 13
5 7
6 10
7 13
8 3
9 6
10 9
11 3
12 3
13 2
14 2
15 2
16 2
17 2
18 2
19 3
21 2
22 2
23 2
24 1
25 2
26 1
28 4
29 3
30 1
32 1
33 1
34 2
35 3
36 2
38 1
39 1
41 1
45 1
52 1
57 1
62 1
66 1
68 1
69 1
73 1
74 1
75 1
89 1
96 1
97 2
101 1
107 1
119 1
135 1
143 1
152 1
167 1
175 1
182 1
186 1
187 1
189 1
227 1
233 1
255 1
508 1
535 1
634 1
1329 1

Phase

Phase Study_Count
Phase 2 210
N/A 106
Phase 1 79
Phase 3 62
Phase 1/Phase 2 46
Phase 2/Phase 3 11
Early Phase 1 9
Phase 4 9

Number of Arms

Number_of_Arms Count_of_Studies
1 247
2 173
3 17
4 10
5 1
6 7
7 1
13 1
37 1
NA 74

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 7.00000 5.000 1.00000 4.00000 1.0000 54.0000 2.000 7.0000
1st Qu. 15.00000 40.000 14.50000 29.00000 36.7500 89.5000 197.000 36.0000
Median 30.00000 67.000 26.50000 49.00000 49.5000 266.0000 300.500 77.0000
Mean 25.44444 1130.029 36.83333 71.24444 100.2656 252.4545 335.629 225.1111
3rd Qu. 37.00000 196.000 40.25000 67.00000 75.7500 355.0000 455.250 402.0000
Max. 40.00000 45386.000 350.00000 515.00000 6452.0000 584.0000 1100.000 642.0000

Trial Group Type

group_type Group_Count
Experimental 595
Active Comparator 131
NA 74
No Intervention 26
Other 19
Placebo Comparator 16
Sham Comparator 1

Intervention Model

intervention_model Study_Count
Single Group Assignment 274
Parallel Assignment 187
NA 43
Sequential Assignment 18
Crossover Assignment 6
Factorial Assignment 4

Primary Purpose

primary_purpose Study_Count
Treatment 440
Diagnostic 29
Prevention 19
Supportive Care 17
Other 8
Screening 8
NA 4
Basic Science 3
Device Feasibility 2
Health Services Research 2

Observational Studies

Studies by Country

Country Study_Count
United States 35
China 10
Netherlands 8
France 5
Denmark 4
NA 4
United Kingdom 4
Germany 3
Ireland 3
Iran, Islamic Republic of 2
Korea, Republic of 2
Australia|France|Germany|Norway|Spain|Sweden|Switzerland|United Kingdom 1
Austria|Belgium|France|Germany|Greece|Italy|Netherlands|Poland|Romania 1
Belgium 1
Canada 1
China|Hong Kong|Taiwan 1
Czech Republic 1
Ireland|Sweden|United Kingdom 1
Italy 1
Japan 1
Spain 1
Taiwan 1
United States|China 1
United States|Puerto Rico 1

Sites per Study

Site_count Study_Count
1 71
2 7
3 3
4 5
5 1
6 1
9 1
10 2
118 1
143 1

Enrollment Metrics

Measure Observational
Min 10.000
1st Qu 87.500
Median 200.000
Mean 9791.935
3rd Qu 1000.000
Max 684815.000

Observation Model

observational_model Study_Count
Cohort 53
Case-Only 17
Case-Control 9
Other 7
NA 5
Case Control 1
Ecologic or Community 1

Time Perspective

time_perspective Study_Count
Prospective 60
Retrospective 21
Cross-Sectional 6
NA 4
Other 2

Registries

Studies by Country

Country Study_Count
United States 4
China 2
France 2
Germany 2
Netherlands 2
Austria 1
Canada|Italy|Netherlands 1
Denmark 1
Korea, Republic of 1
Taiwan 1

Sites per Study

Site_count Study_Count
1 13
3 1
6 1
16 1
75 1

Enrollment Metrics

Measure Registries
Min 45.00
1st Qu 140.00
Median 400.00
Mean 60339.35
3rd Qu 1500.00
Max 999999.00

Registry Model

observational_model Study_Count
Cohort 13
Case-Only 2
Case-Control 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 16
Other 1

Follow-up

target_duration Study_Count
5 Years 7
1 Year 2
2 Years 2
3 Years 2
2 Months 1
24 Months 1
36 Months 1
80 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT00342472 Environmental and Biological Monitoring Pilot Study for Polycyclic Aromatic Hydrocarbons in Linxian, China https://ClinicalTrials.gov/show/NCT00342472 Completed National Institutes of Health Clinical Center (CC) NA
NCT03410758 Predictive Factors of Survival With and Without Repetition With 5 and 10 Years Curative Post-oesophagectomy for Cancer of the Oesophagus https://ClinicalTrials.gov/show/NCT03410758 Completed University Hospital, Brest 2017-12-31
NCT03396614 Detection of (Sub)Clinical Toxicity in Irradiated vs. Non-irradiated Surgically Treated Esophageal Cancer Patients: a Pilot Study (CROSS SECT) https://ClinicalTrials.gov/show/NCT03396614 Recruiting University Medical Center Groningen 2020-10-01
NCT04136236 Automatic Diagnosis of Early Esophageal Squamous Neoplasia Using pCLE With AI https://ClinicalTrials.gov/show/NCT04136236 Recruiting Shandong University 2019-12-01
NCT03298204 Definitive (Chemo)Radiotherapy for Patients With Esophageal Cancer - 3JECROG R-01 https://ClinicalTrials.gov/show/NCT03298204 Completed Chinese Academy of Medical Sciences 2017-09-30
NCT03237130 Prediction of Lymphatic Metastasis in Esophageal Cancer by CT Radiomics https://ClinicalTrials.gov/show/NCT03237130 Recruiting Beijing Cancer Hospital 2019-11-07
NCT03231462 Impact of Perioperative Physical Activity on Postoperative Pulmonary Complications and Quality of Life Among Esophageal Cancer Patients https://ClinicalTrials.gov/show/NCT03231462 Recruiting Samsung Medical Center 2019-12-31
NCT03133286 Radiotherapy Assessments During Intervention ANd Treatment (RADIANT) https://ClinicalTrials.gov/show/NCT03133286 Recruiting DxTerity Diagnostics 2019-09-06
NCT03108885 Measuring Cell Free DNA During the Course of Treatment for Esophageal Cancer as a Marker of Response and Recurrence https://ClinicalTrials.gov/show/NCT03108885 Enrolling by invitation Mayo Clinic 2022-03-31
NCT02839109 PET-CT vs DWI-MRI in Response Evaluation in Esophageal Cancer https://ClinicalTrials.gov/show/NCT02839109 Completed University Medical Center Groningen 2017-08-31
NCT02703142 Endoscopic Evaluation After Esophagectomy https://ClinicalTrials.gov/show/NCT02703142 Completed Nagasaki University 2016-10-31
NCT02530983 Mayo Clinic Conduit Report Card Questionnaires (CONDUIT) https://ClinicalTrials.gov/show/NCT02530983 Recruiting Mayo Clinic 2020-12-31
NCT02495337 Tissue Collection Protocol https://ClinicalTrials.gov/show/NCT02495337 Recruiting University Health Network, Toronto 2021-12-31
NCT02452021 Pencil Beam Scanning Proton Radiotherapy for Esophageal Cancer https://ClinicalTrials.gov/show/NCT02452021 Active, not recruiting Mayo Clinic 2019-08-30
NCT02427269 UNC Barrett’s Esophagus and Esophageal Cancer Biorepository https://ClinicalTrials.gov/show/NCT02427269 Active, not recruiting University of North Carolina, Chapel Hill 2025-05-31
NCT02385604 The Predictive Value of CT-PET in Esophageal Cancer https://ClinicalTrials.gov/show/NCT02385604 Completed St. James’s Hospital, Ireland 2016-01-31
NCT02372929 Relationship Between Endoscopic Ultrasound Staging and Degree of Stricture in Esophageal Cancer https://ClinicalTrials.gov/show/NCT02372929 Completed AdventHealth 2014-04-30
NCT02239328 A Study of Patient-reported Outcomes in Patients With Lung or Esophageal Cancer https://ClinicalTrials.gov/show/NCT02239328 Completed University of Virginia 2017-06-30
NCT02139488 Organ Motion and Early Tumor Response Measurement https://ClinicalTrials.gov/show/NCT02139488 Completed The Netherlands Cancer Institute 2018-12-31
NCT01269970 Early Metabolic Response in Locally Advanced Esophageal Cancer Undergoing Induction Chemoradiotherapy https://ClinicalTrials.gov/show/NCT01269970 Completed Universitaire Ziekenhuizen Leuven 2008-07-31
NCT00242723 Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining https://ClinicalTrials.gov/show/NCT00242723 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT01927016 Outcomes After Esophageal Cancer Surgery https://ClinicalTrials.gov/show/NCT01927016 Completed University Hospital, Lille 2013-04-30
NCT01858805 Circulating Tumor Cells as a Biomarker for Preoperative Prognostic Staging in Patients With Esophageal Cancer https://ClinicalTrials.gov/show/NCT01858805 Completed Universitätsklinikum Hamburg-Eppendorf 2014-04-30
NCT01836913 Value of PET-CT in Radiation Treatment Planning for Patients With Esophageal Cancer https://ClinicalTrials.gov/show/NCT01836913 Completed University Medical Center Groningen 2012-04-30
NCT01783158 Chromoendoscopy to Detect Early Synchronous Second Primary Esophageal Carcinoma https://ClinicalTrials.gov/show/NCT01783158 Completed University Hospital Ostrava 2012-11-30
NCT01770275 UICC Classification of Esophageal Cancer https://ClinicalTrials.gov/show/NCT01770275 Completed Universitätsklinikum Hamburg-Eppendorf 2013-01-31
NCT01766986 Staging and Outcome Depending on Surgical Treatment in Adenocarcinomas of the Oesophagogastric Junction https://ClinicalTrials.gov/show/NCT01766986 Completed Universitätsklinikum Hamburg-Eppendorf 2013-01-31
NCT01766349 Effect of CCRT on Respiratory Performance and Functional Capacity in Esophagus Cancer Patients https://ClinicalTrials.gov/show/NCT01766349 Completed Far Eastern Memorial Hospital 2013-09-30
NCT01640860 Concurrent Chemoradiotherapy With Docetaxel and Cisplatin in Esophageal Cancer https://ClinicalTrials.gov/show/NCT01640860 Completed Chonnam National University Hospital 2009-12-31
NCT01558648 Quality of Life Outcomes Following Minimally Invasive and Open Esophagectomy for Esophageal Cancer https://ClinicalTrials.gov/show/NCT01558648 Active, not recruiting Memorial Sloan Kettering Cancer Center 2021-03-31
NCT01525953 Complete Clinical Responders to Definite Chemoradiation in Esophageal Cancer : a Survival Analysis https://ClinicalTrials.gov/show/NCT01525953 Completed Centre Oscar Lambret 2012-01-31
NCT01444456 Assessment of Quality of Life in Patients With Symptomatic Chemotherapy-induced Anaemia https://ClinicalTrials.gov/show/NCT01444456 Completed Amgen 2013-08-31
NCT01416714 Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy https://ClinicalTrials.gov/show/NCT01416714 Recruiting University of Chicago 2025-01-31
NCT01325883 The Effect of Chemotherapy and Surgery for Cancer on Exercise Capacity https://ClinicalTrials.gov/show/NCT01325883 Completed Liverpool University Hospitals NHS Foundation Trust 2014-08-31
NCT04214119 EsophaCap for the Detection of Early Esophageal Carcinoma https://ClinicalTrials.gov/show/NCT04214119 Recruiting Johns Hopkins University 2025-12-19
NCT04183218 Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes in Non-metastatic, Non-recurrent Lung and Esophageal Cancer Patients https://ClinicalTrials.gov/show/NCT04183218 Recruiting Mayo Clinic 2021-09-23
NCT04151524 Classification of Adenocarcinoma of the Esophagogastric Junction https://ClinicalTrials.gov/show/NCT04151524 Active, not recruiting St. James’s Hospital, Ireland 2019-12-25
NCT04074447 The Efficacy of Immunodetection Point Inhibitors for Advanced Esophageal Cancer https://ClinicalTrials.gov/show/NCT04074447 Recruiting Sun Yat-sen University 2020-05-31
NCT04027543 Neoadjuvant Chemotherapy or Chemoradiotherapy in Resectable Oesophageal Carcinoma(NewEC Study) https://ClinicalTrials.gov/show/NCT04027543 Completed Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 2019-12-01
NCT04014465 Monitoring Efficacy of Radiotherapy in Lung Cancer and Esophageal Cancer https://ClinicalTrials.gov/show/NCT04014465 Recruiting Chinese Academy of Medical Sciences 2022-06-30
NCT03937362 Pre-Surgery If Needed for Oesophageal Cancer https://ClinicalTrials.gov/show/NCT03937362 Recruiting Shanghai Chest Hospital 2022-08-08
NCT03922230 Exploration and Verification of DNA Methylolation in Early Screening of Esophageal Cancer https://ClinicalTrials.gov/show/NCT03922230 Recruiting Nanfang Hospital of Southern Medical University 2020-12-31
NCT03347162 Muscle Dysfunction in Gastrointestinal or Hepatobiliary Cancer https://ClinicalTrials.gov/show/NCT03347162 Recruiting Rigshospitalet, Denmark 2021-12-31
NCT03896958 The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology) https://ClinicalTrials.gov/show/NCT03896958 Recruiting SpeciCare 2021-03-12
NCT03835663 The Bacterial Composition of the Stomach in Reflux Disease https://ClinicalTrials.gov/show/NCT03835663 Recruiting Imperial College London 2019-06-01
NCT03743883 EffectiveNess of Low-dose Aspirin in Prevention of Cancer in the Stomach and Oesophagus (GastrointEstinal Cancer Prevention) - United Kingdom (“ENgAGE - UK”): Study to Evaluate the Risk of Cancer in the Stomach and Oesophagus Among New Users of Low-dose Aspirin Using the THIN Database in the UK https://ClinicalTrials.gov/show/NCT03743883 Completed Bayer 2019-04-15
NCT03712774 Prospective Observational Trial to Evaluate Quality of Life After Neoadjuvant or Definitive Chemoradiation in Patients With Esophageal Cancer https://ClinicalTrials.gov/show/NCT03712774 Recruiting Ludwig-Maximilians - University of Munich 2021-12-31
NCT03707574 Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study https://ClinicalTrials.gov/show/NCT03707574 Recruiting National Cancer Institute (NCI) 2023-05-01
NCT03646409 Venous Thromboembolism and Bleeding Risk in Patients With Esophageal Cancer https://ClinicalTrials.gov/show/NCT03646409 Completed Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2018-10-01
NCT03619317 Impact of Cancer Therapy on Myocardial Function in Patients With Esophagus Cancer https://ClinicalTrials.gov/show/NCT03619317 Recruiting Aarhus University Hospital Skejby 2020-06-30
NCT03596411 The Detection of Barrett’s Esophagus by Gastrointestinal Endoscopy Prevents Esophageal Carcinoma in Morbid Obese After Sleeve Gastrectomy https://ClinicalTrials.gov/show/NCT03596411 Recruiting Centre Hospitalier Universitaire de Nice 2023-05-17
NCT03541629 Audit of the Spanish EURECCA Esophagogastric Cancer Registry https://ClinicalTrials.gov/show/NCT03541629 Recruiting Parc de Salut Mar 2018-11-30
NCT03526328 DCLK1 as a Marker/Indicator of Stem Cell Response in Barrett’s Esophagus/Esophageal Adenocarcinoma https://ClinicalTrials.gov/show/NCT03526328 Completed University of Oklahoma 2019-08-13
NCT03474341 Preoperative Image-guided Identification of Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer https://ClinicalTrials.gov/show/NCT03474341 Recruiting UMC Utrecht 2020-08-31
NCT03467529 Evaluation of Full-field Coherence Tomography for ex Vivo Staging and Assessment of Superficial Esophageal Squamous Carcinoma: a Pilot Study https://ClinicalTrials.gov/show/NCT03467529 Recruiting Nantes University Hospital 2021-04-30
NCT03462524 Neoadjuvant Therapy for Esophageal Cancer and Cardiopulmonary Physiology https://ClinicalTrials.gov/show/NCT03462524 Completed St. James’s Hospital, Ireland 2016-01-01
NCT03461341 European iNvestigation of SUrveillance After Resection for Esophageal Cancer https://ClinicalTrials.gov/show/NCT03461341 Completed St. James’s Hospital, Ireland 2015-06-01
NCT03428074 A Observational Study to Compare Effectiveness and Safety of the Surgeries in Patients With Esophageal Cancer https://ClinicalTrials.gov/show/NCT03428074 Completed Chinese PLA General Hospital 2018-03-30
NCT01216813 Study of Physical and Psychosocial Rehabilitation Needs of Patients After Diagnosis and Treatment of Upper Gastrointestinal Cancer or Gynecological Cancer https://ClinicalTrials.gov/show/NCT01216813 Completed National Cancer Institute (NCI) 2010-10-31
NCT01156831 PET-CT Based Radiotherapy in Esophageal Cancer Patients https://ClinicalTrials.gov/show/NCT01156831 Completed Maastricht Radiation Oncology 2011-05-31
NCT01077817 Observational Study of Incidence Rates of Esophageal Cancer in Women Taking Medications for the Prevention or Treatment of Osteoporosis (MK-0217A-352) https://ClinicalTrials.gov/show/NCT01077817 Completed Merck Sharp & Dohme Corp. 2012-02-16
NCT01035398 Genetic and Environmental Risk Factors Related to Esophageal Cancer https://ClinicalTrials.gov/show/NCT01035398 Recruiting Massachusetts General Hospital 2022-06-30
NCT00900419 Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers https://ClinicalTrials.gov/show/NCT00900419 Recruiting University of Colorado, Denver 2020-09-30
NCT00900094 UMCC 003 Cancer-Related Protein Biomarkers in Blood and Tumor Tissue of Patients With Cancer https://ClinicalTrials.gov/show/NCT00900094 Completed University of Michigan Rogel Cancer Center 2006-12-31
NCT00899626 Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Patients and Healthy Participants https://ClinicalTrials.gov/show/NCT00899626 Recruiting Vanderbilt University Medical Center 2030-10-31
NCT00898495 Genes in Predicting Outcome in Patients With Esophageal Cancer Treated With Cisplatin, Radiation Therapy, and Surgery https://ClinicalTrials.gov/show/NCT00898495 Completed Eastern Cooperative Oncology Group 2008-12-31
NCT04161781 A Study of PET Scans With the Radioactive Tracer 18F-BMS-986229 in Patients With Esophageal, Stomach, or Gastroesophageal Junction Cancer https://ClinicalTrials.gov/show/NCT04161781 Recruiting Memorial Sloan Kettering Cancer Center 2021-11-12
NCT00836992 Quality of Life in Patients Undergoing Radiation Therapy for Primary Lung Cancer, Head and Neck Cancer, or Gastrointestinal Cancer https://ClinicalTrials.gov/show/NCT00836992 Completed Mayo Clinic 2011-09-15
NCT03095209 Observation Study of Patients With Non-Small Cell Lung Cancer and Esophageal Cancer Treated With Chemo-Radiation Followed by Surgery https://ClinicalTrials.gov/show/NCT03095209 Active, not recruiting Fox Chase Cancer Center 2020-09-01
NCT01635595 Nodal Status in Adenocarcinoma of the Esophagus an Cardia https://ClinicalTrials.gov/show/NCT01635595 Completed University of Bologna NA
NCT00450788 Esophageal Cancer in Northeastern Iran https://ClinicalTrials.gov/show/NCT00450788 Active, not recruiting National Institutes of Health Clinical Center (CC) NA
NCT03829098 TreatmENT of AnastomotiC Leakage After Esophagectomy https://ClinicalTrials.gov/show/NCT03829098 Recruiting Radboud University 2019-10-01
NCT00747448 CryoSpray Ablation (TM) GI Patient Registry https://ClinicalTrials.gov/show/NCT00747448 Completed CSA Medical, Inc. 2013-06-30
NCT00727376 Evaluation of Polyflex Stenting in Esophageal Cancer Patients https://ClinicalTrials.gov/show/NCT00727376 Completed University of Louisville 2011-02-28
NCT00716157 Incidence and Patterns of Nausea/Vomiting With Combined Chemotherapy and Radiation https://ClinicalTrials.gov/show/NCT00716157 Completed Thomas Jefferson University 2008-08-31
NCT00686569 Mediastinal Microdialysis in Patients With Oesophageal or Cardia Cancer Treated by Resection https://ClinicalTrials.gov/show/NCT00686569 Completed Odense University Hospital 2008-10-31
NCT00660205 Venous Thromboembolism and Haemostatic Disturbances in Patients With Upper Gastrointestinal Cancer https://ClinicalTrials.gov/show/NCT00660205 Completed University of Aarhus 2011-02-28
NCT00598117 Quality Of Life Outcomes Following Treatment for Esophageal Cancer https://ClinicalTrials.gov/show/NCT00598117 Completed Memorial Sloan Kettering Cancer Center 2013-06-30
NCT00591981 Thoracic OncoGeriatric Assessment (TOGA) Trials https://ClinicalTrials.gov/show/NCT00591981 Completed University of Wisconsin, Madison 2012-08-31
NCT00583934 Is Screening for Esophageal Pathology in Asymptomatic Patients Post-Treatment for Head and Neck Cancer Beneficial? https://ClinicalTrials.gov/show/NCT00583934 Completed University of California, Davis 2009-11-30
NCT00533884 Neurocognitive Functioning in Patients With Newly Diagnosed Upper Aerodigestive Tract Cancer Receiving Treatment at Henry-Joyce Cancer Clinic https://ClinicalTrials.gov/show/NCT00533884 Completed Vanderbilt University Medical Center 2010-05-31
NCT00502502 Assessment of Symptom-Related Cytokines in Lung and Gastrointestinal (GI) Cancer Patients https://ClinicalTrials.gov/show/NCT00502502 Completed M.D. Anderson Cancer Center 2010-07-31
NCT00431756 Novel Biomarkers in the Neoplastic Progression of Barrett’s Esophagus https://ClinicalTrials.gov/show/NCT00431756 Active, not recruiting Johns Hopkins University 2022-06-30
NCT00341523 Early Detection of Esophageal Cancer https://ClinicalTrials.gov/show/NCT00341523 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT00341276 Esophageal Cancer Genetics Studies https://ClinicalTrials.gov/show/NCT00341276 Completed National Institutes of Health Clinical Center (CC) NA
NCT00310115 Motivational Counseling in Preventing Smoking Relapse After Pregnancy in Pregnant Women Who Quit Smoking During Pregnancy https://ClinicalTrials.gov/show/NCT00310115 Completed M.D. Anderson Cancer Center 2016-08-31
NCT00288119 Genetic Determinants of Barrett’s Esophagus and Esophageal Adenocarcinoma https://ClinicalTrials.gov/show/NCT00288119 Recruiting University Hospitals Cleveland Medical Center 2022-04-30
NCT00260585 Esophageal Cancer Risk Registry https://ClinicalTrials.gov/show/NCT00260585 Recruiting University of Pittsburgh 2050-12-31
NCT00260559 Outcomes After Esophagectomy With a Focus on Minimally Invasive Esophagectomy and Quality of Life https://ClinicalTrials.gov/show/NCT00260559 Recruiting University of Pittsburgh 2050-12-31
NCT00798746 Quality of Life After Esophagectomy for Cancer https://ClinicalTrials.gov/show/NCT00798746 Completed M.D. Anderson Cancer Center 2010-05-31
NCT00003321 Quality-of-Life Assessment of Patients Who Have Cancer of the Esophagus https://ClinicalTrials.gov/show/NCT00003321 Completed European Organisation for Research and Treatment of Cancer - EORTC 2001-08-31
NCT00339742 Stomach and Esophageal Cancers in Northern Iran https://ClinicalTrials.gov/show/NCT00339742 Active, not recruiting National Institutes of Health Clinical Center (CC) NA
NCT00001603 The Effects of Upper Airway and Digestive Tract Tumors on the Immune System https://ClinicalTrials.gov/show/NCT00001603 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03301493 Genomic Testing and Resulting Medical Decisions https://ClinicalTrials.gov/show/NCT03301493 Recruiting Arbeitsgemeinschaft medikamentoese Tumortherapie 2019-12-31
NCT03222895 Distribution of Lymph Node Metastases in Esophageal Carcinoma https://ClinicalTrials.gov/show/NCT03222895 Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2021-12-01
NCT03140189 Robot-assisted IVOR-LEWIS Esophagectomy https://ClinicalTrials.gov/show/NCT03140189 Active, not recruiting Ruijin Hospital 2019-07-10
NCT03120572 Effect of Concurrent Chemoradiation Therapy on Respiratory Muscle Performance, Lung Function and Functional Capacity in Patients With Local Esophagus Cancer https://ClinicalTrials.gov/show/NCT03120572 Completed Mackay Memorial Hospital 2016-02-29
NCT03081988 Prediction Model of Response for CCRT in Esophageal Cancer https://ClinicalTrials.gov/show/NCT03081988 Recruiting Kyungpook National University Hospital 2020-12-31
NCT02583087 ESD for the Treatment of Early Barrett’s Neoplasia https://ClinicalTrials.gov/show/NCT02583087 Recruiting Hôpital Cochin 2019-04-30
NCT02454790 Standard Follow-Up Program (SFP) for Patients With Esophageal Cancer https://ClinicalTrials.gov/show/NCT02454790 Recruiting University Medical Center Groningen 2025-01-31
NCT02305043 Identification of Biomarkers for Prediction of Response or Resistance Against Target Therapy in Gastric Cancer https://ClinicalTrials.gov/show/NCT02305043 Completed University of Leipzig 2018-01-31
NCT02012699 Integrated Cancer Repository for Cancer Research https://ClinicalTrials.gov/show/NCT02012699 Recruiting University of Nebraska 2099-12-31
NCT01802203 trūFreeze® Spray Cryotherapy Patient Registry https://ClinicalTrials.gov/show/NCT01802203 Active, not recruiting US Endoscopy Group Inc. 2021-08-31
NCT01780961 Esophageal Cancer Tissue Banking https://ClinicalTrials.gov/show/NCT01780961 Recruiting Washington University School of Medicine 2025-06-30
NCT04290806 Registry Platform Gastric/Esophageal Cancer (SAPHIR) https://ClinicalTrials.gov/show/NCT04290806 Recruiting iOMEDICO AG 2024-12-31
NCT04145726 Frailty In Thoracic Surgery for Esophageal Cancer https://ClinicalTrials.gov/show/NCT04145726 Recruiting Rigshospitalet, Denmark 2020-10-31
NCT04075305 The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study https://ClinicalTrials.gov/show/NCT04075305 Recruiting UMC Utrecht 2024-02-01
NCT03674801 Status of Superficial Esophageal Cancers Treated by Endoscopy “OESOFARE” https://ClinicalTrials.gov/show/NCT03674801 Recruiting Nantes University Hospital 2025-09-30
NCT03635619 The Application of 3T MRI in Esophageal Cancer https://ClinicalTrials.gov/show/NCT03635619 Recruiting Henan Cancer Hospital 2023-12-30
NCT03452774 SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry https://ClinicalTrials.gov/show/NCT03452774 Recruiting Massive Bio, Inc. 2021-12-31